A family of anticancer drugs that interferes with the cell's DNA and inhibits cancer cell growth.

  Chemicals that transfer alkyl (methyl, ethyl, etc.) groups to the bases in DNA.

Definition: (AL-kah-LIE-teen) A family of anticancer drugs that interferes with the cell's DNA and inhibits cancer cell growth. Drugs that are alkylating agents are often used in chemotherapy.

Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as Antineoplastic Agents, but most are very toxic [..]

A class of Drugs that differs from other Alkylating Agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a re [..]

Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic [..]

Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agent, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. (12 Dec 1998)

A family of anticancer drugs (including nitrosoureas) that combine with a cancer cell's DNA to prevent normal cell division. Alkylating agents include busulfan, carmustine, carzelesin, cyclophosphamide (also called Cytoxan), ifosfamide, lomustine, melphalan, porfiromycin and semustine.

 Substances that interfere with the metabolism and growth of cells, so used as drugs to treat some cancers; examples are chlorambucil and cyclophosphamide